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Modular synthesis of the pyrimidine core of the manzacidins by divergent Tsuji–Trost coupling
The design, development and application of an efficient procedure for the concise synthesis of the 1,3-syn- and anti-tetrahydropyrimidine cores of manzacidins are reported. The intramolecular allylic substitution reaction of a readily available joint urea-type substrate enables the facile preparatio...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902044/ https://www.ncbi.nlm.nih.gov/pubmed/27340499 http://dx.doi.org/10.3762/bjoc.12.107 |