Overcoming resistance to TRAIL-induced apoptosis in solid tumor cells by simultaneously targeting death receptors, c-FLIP and IAPs

The discovery of the TRAIL protein and its death receptors DR4/5 changed the horizon of cancer research because TRAIL specifically kills cancer cells. However, the validity of TRAIL-based cancer therapies has yet to be established, as most cancer cells are TRAIL-resistant. In this report, we demonst...

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Detalles Bibliográficos
Autores principales: HUANG, YING, YANG, XIANG, XU, TIANRUI, KONG, QINGHONG, ZHANG, YAPING, SHEN, YUEHAI, WEI, YUNLIN, WANG, GUANLIN, CHANG, KWEN-JEN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
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Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902065/
https://www.ncbi.nlm.nih.gov/pubmed/27210546
http://dx.doi.org/10.3892/ijo.2016.3525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902065/
https://www.ncbi.nlm.nih.gov/pubmed/27210546
http://dx.doi.org/10.3892/ijo.2016.3525

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