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A CD13 inhibitor, ubenimex, synergistically enhances the effects of anticancer drugs in hepatocellular carcinoma

Cancer stem cells (CSCs) were reported to be involved in resistance to chemo/radiation therapy. We previously reported that CD13 was both a marker of CSCs and a candidate therapeutic target in HCC. In the present study, we explored the antitumor effect of a combined therapy, where ubenimex, a CD13 i...

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Detalles Bibliográficos
Autores principales: YAMASHITA, MASAFUMI, WADA, HIROSHI, EGUCHI, HIDETOSHI, OGAWA, HISATAKA, YAMADA, DAISAKU, NODA, TAKEHIRO, ASAOKA, TADAFUMI, KAWAMOTO, KOICHI, GOTOH, KUNIHITO, UMESHITA, KOJI, DOKI, YUICHIRO, MORI, MASAKI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902077/
https://www.ncbi.nlm.nih.gov/pubmed/27121124
http://dx.doi.org/10.3892/ijo.2016.3496