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Verapamil inhibits tumor progression of chemotherapy-resistant pancreatic cancer side population cells

Tumor side population (SP) cells display stem-like properties that can be modulated by treatment with the calcium channel blocker verapamil. Verapamil can enhance the cytotoxic effects of chemotherapeutic drugs and multi-drug resistance by targeting the transport function of the P-glycoprotein (P-gp...

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Detalles Bibliográficos
Autores principales: ZHAO, LU, ZHAO, YUE, SCHWARZ, BETTINA, MYSLIWIETZ, JOSEF, HARTIG, ROLAND, CAMAJ, PETER, BAO, QI, JAUCH, KARL-WALTER, GUBA, MAKUS, ELLWART, JOACHIM WALTER, NELSON, PETER JON, BRUNS, CHRISTIANE JOSEPHINE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902079/
https://www.ncbi.nlm.nih.gov/pubmed/27177126
http://dx.doi.org/10.3892/ijo.2016.3512