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Verapamil inhibits tumor progression of chemotherapy-resistant pancreatic cancer side population cells
Tumor side population (SP) cells display stem-like properties that can be modulated by treatment with the calcium channel blocker verapamil. Verapamil can enhance the cytotoxic effects of chemotherapeutic drugs and multi-drug resistance by targeting the transport function of the P-glycoprotein (P-gp...
Autores principales: | ZHAO, LU, ZHAO, YUE, SCHWARZ, BETTINA, MYSLIWIETZ, JOSEF, HARTIG, ROLAND, CAMAJ, PETER, BAO, QI, JAUCH, KARL-WALTER, GUBA, MAKUS, ELLWART, JOACHIM WALTER, NELSON, PETER JON, BRUNS, CHRISTIANE JOSEPHINE |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902079/ https://www.ncbi.nlm.nih.gov/pubmed/27177126 http://dx.doi.org/10.3892/ijo.2016.3512 |
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