Cargando…

Self‐Assembly of Disorazole C(1) through a One‐Pot Alkyne Metathesis Homodimerization Strategy

Alkyne metathesis is increasingly explored as a reliable method to close macrocyclic rings, but there are no prior examples of an alkyne‐metathesis‐based homodimerization approach to natural products. In this approach to the cytotoxic C(2)‐symmetric marine‐derived bis(lactone) disorazole C(1), a hig...

Descripción completa

Detalles Bibliográficos
Autores principales: Ralston, Kevin J., Ramstadius, H. Clinton, Brewster, Richard C., Niblock, Helen S., Hulme, Alison N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY‐VCH Verlag 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902119/
https://www.ncbi.nlm.nih.gov/pubmed/27346897
http://dx.doi.org/10.1002/ange.201501922