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Hexavalent Chromium (Cr(VI)) Down-Regulates Acetylation of Histone H4 at Lysine 16 through Induction of Stressor Protein Nupr1
The environmental and occupational carcinogen Hexavalent Chromium (Cr(VI)) has been shown to cause lung cancer in humans when inhaled. In spite of a considerable research effort, the mechanisms of Cr(VI)-induced carcinogenesis remain largely unknown. Nupr1 (nuclear protein 1) is a small, highly basi...
Autores principales: | Chen, Danqi, Kluz, Thomas, Fang, Lei, Zhang, Xiaoru, Sun, Hong, Jin, Chunyuan, Costa, Max |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902237/ https://www.ncbi.nlm.nih.gov/pubmed/27285315 http://dx.doi.org/10.1371/journal.pone.0157317 |
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