Mathematical Modeling Predicts that Increased HSV-2 Shedding in HIV-1 Infected Persons Is Due to Poor Immunologic Control in Ganglia and Genital Mucosa

A signature feature of HIV infection is poor control of herpes virus infections, which reactivate from latency and cause opportunistic infections. While the general mechanism underlying this observation is deficient CD4+T-cell function, it is unknown whether increased severity of herpes virus infect...

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Detalles Bibliográficos
Autores principales: Schiffer, Joshua T., Swan, David A., Magaret, Amalia, Schacker, Timothy W., Wald, Anna, Corey, Lawrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902308/
https://www.ncbi.nlm.nih.gov/pubmed/27285483
http://dx.doi.org/10.1371/journal.pone.0155124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902308/
https://www.ncbi.nlm.nih.gov/pubmed/27285483
http://dx.doi.org/10.1371/journal.pone.0155124

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