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Functional Analysis of SNPs in the ERCC5 Promoter in Advanced Colorectal Cancer Patients Treated With Oxaliplatin-Based Chemotherapy

The promoter is the center for regulation of gene transcription due to containing numerous transcription factor binding sites. The aim of the study was to determine whether genetic variations at excision repair cross complementation group 5 (ERCC5) promoter could affect transcription factor binding...

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Detalles Bibliográficos
Autores principales: Chen, Jianfang, Luo, Xi, Xie, Ganfeng, Chen, Keli, Jiang, Heng, Pan, Feng, Li, Jianjun, Ruan, Zhihua, Pang, Xueli, Liang, Houjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902533/
https://www.ncbi.nlm.nih.gov/pubmed/27175691
http://dx.doi.org/10.1097/MD.0000000000003652