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N(ε)-Carboxymethyl Modification of Lysine Residues in Pathogenic Prion Isoforms
The most prominent hallmark of prion diseases is prion protein conversion and the subsequent deposition of the altered prions, PrP(Sc), at the pathological sites of affected individuals, particularly in the brain. A previous study has demonstrated that the N-terminus of the pathogenic prion isoform...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902843/ https://www.ncbi.nlm.nih.gov/pubmed/25983034 http://dx.doi.org/10.1007/s12035-015-9200-8 |