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Disruption of the Golgi protein Otg1 gene causes defective hormone secretion and aberrant glucose homeostasis in mice

BACKGROUND: Concerted hormone secretion is essential for glucose homeostasis and growth. The oocyte testis gene 1 (Otg1) has limited information in mammals before. Human OTG1 has been identified as an antigen associated with cutaneous T cell lymphoma, while worm Otg1 is recently reported to be a ves...

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Detalles Bibliográficos
Autores principales: Wang, Guangxue, Li, Rongbo, Yang, Ying, Cai, Liang, Ding, Sheng, Xu, Tian, Han, Min, Wu, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902905/
https://www.ncbi.nlm.nih.gov/pubmed/27293546
http://dx.doi.org/10.1186/s13578-016-0108-4