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Disruption of the Golgi protein Otg1 gene causes defective hormone secretion and aberrant glucose homeostasis in mice
BACKGROUND: Concerted hormone secretion is essential for glucose homeostasis and growth. The oocyte testis gene 1 (Otg1) has limited information in mammals before. Human OTG1 has been identified as an antigen associated with cutaneous T cell lymphoma, while worm Otg1 is recently reported to be a ves...
Autores principales: | Wang, Guangxue, Li, Rongbo, Yang, Ying, Cai, Liang, Ding, Sheng, Xu, Tian, Han, Min, Wu, Xiaohui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902905/ https://www.ncbi.nlm.nih.gov/pubmed/27293546 http://dx.doi.org/10.1186/s13578-016-0108-4 |
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