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Effects on muscle tissue remodeling and lipid metabolism in muscle tissue from adult patients with polymyositis or dermatomyositis treated with immunosuppressive agents

BACKGROUND: Polymyositis (PM) and dermatomyositis (DM) are autoimmune muscle diseases, conventionally treated with high doses of glucocorticoids in combination with immunosuppressive drugs. Treatment is often dissatisfying, with persisting muscle impairment. We aimed to investigate molecular mechani...

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Detalles Bibliográficos
Autores principales: Loell, Ingela, Raouf, Joan, Chen, Yi-Wen, Shi, Rongye, Nennesmo, Inger, Alexanderson, Helene, Dastmalchi, Maryam, Nagaraju, Kanneboyina, Korotkova, Marina, Lundberg, Ingrid E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902919/
https://www.ncbi.nlm.nih.gov/pubmed/27287443
http://dx.doi.org/10.1186/s13075-016-1033-y