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Perinatal HIV-1 transmission: Fc gamma receptor variability associates with maternal infectiousness and infant susceptibility

BACKGROUND: Accumulating data suggest that immune effector functions mediated through the Fc portion of HIV-1-specific immunoglobulin G (IgG) are a key component of HIV-1 protective immunity, affecting both disease progression and HIV-1 acquisition. Through studying Fc gamma receptor (FcγR) variants...

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Detalles Bibliográficos
Autores principales: Lassaunière, Ria, Musekiwa, Alfred, Gray, Glenda E., Kuhn, Louise, Tiemessen, Caroline T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902924/
https://www.ncbi.nlm.nih.gov/pubmed/27287460
http://dx.doi.org/10.1186/s12977-016-0272-y