Cargando…

Phytanic acid activates NADPH oxidase through transactivation of epidermal growth factor receptor in vascular smooth muscle cells

BACKGROUND: Phytanic acid (PA) has been implicated in development of cancer and its defective metabolism is known to cause life-threatening conditions, such as Refsum disease, in children. To explore molecular mechanisms of phytanic acid-induced cellular pathology, we investigated its effect on NADP...

Descripción completa

Detalles Bibliográficos
Autores principales: Dhaunsi, Gursev S., Alsaeid, Mayra, Akhtar, Saghir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902935/
https://www.ncbi.nlm.nih.gov/pubmed/27287039
http://dx.doi.org/10.1186/s12944-016-0273-9