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Developmental interneuron subtype deficits after targeted loss of Arx

BACKGROUND: Aristaless-related homeobox (ARX) is a paired-like homeodomain transcription factor that functions primarily as a transcriptional repressor and has been implicated in neocortical interneuron specification and migration. Given the role interneurons appear to play in numerous human conditi...

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Detalles Bibliográficos
Autores principales: Marsh, Eric D., Nasrallah, MacLean Pancoast, Walsh, Caroline, Murray, Kaitlin A., Nicole Sunnen, C., McCoy, Almedia, Golden, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902966/
https://www.ncbi.nlm.nih.gov/pubmed/27287386
http://dx.doi.org/10.1186/s12868-016-0265-8