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Enabling low cost biopharmaceuticals: high level interferon alpha-2b production in Trichoderma reesei
BACKGROUND: The filamentous fungus Trichoderma reesei has tremendous capability to secrete over 100 g/L of proteins and therefore it would make an excellent host system for production of high levels of therapeutic proteins at low cost. We have developed T. reesei strains suitable for production of t...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902970/ https://www.ncbi.nlm.nih.gov/pubmed/27287473 http://dx.doi.org/10.1186/s12934-016-0508-5 |