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Enabling low cost biopharmaceuticals: high level interferon alpha-2b production in Trichoderma reesei

BACKGROUND: The filamentous fungus Trichoderma reesei has tremendous capability to secrete over 100 g/L of proteins and therefore it would make an excellent host system for production of high levels of therapeutic proteins at low cost. We have developed T. reesei strains suitable for production of t...

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Detalles Bibliográficos
Autores principales: Landowski, Christopher P., Mustalahti, Eero, Wahl, Ramon, Croute, Laurence, Sivasiddarthan, Dhinakaran, Westerholm-Parvinen, Ann, Sommer, Benjamin, Ostermeier, Christian, Helk, Bernhard, Saarinen, Juhani, Saloheimo, Markku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902970/
https://www.ncbi.nlm.nih.gov/pubmed/27287473
http://dx.doi.org/10.1186/s12934-016-0508-5