Cargando…

Urea and protein carbamylation in ESRD: Surrogate markers or partners in crime?

Protein carbamylation may result from chronic exposure to elevated levels of urea in patients with chronic kidney disease. Carbamylation could cause conformational changes in proteins resulting in alterations in binding sites and disturbances in cellular functions. Elevated levels of carbamylated pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Velasquez, Manuel T, Ramezani, Ali, Raj, Dominic S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4903078/
https://www.ncbi.nlm.nih.gov/pubmed/26024026
http://dx.doi.org/10.1038/ki.2015.78