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Urea and protein carbamylation in ESRD: Surrogate markers or partners in crime?
Protein carbamylation may result from chronic exposure to elevated levels of urea in patients with chronic kidney disease. Carbamylation could cause conformational changes in proteins resulting in alterations in binding sites and disturbances in cellular functions. Elevated levels of carbamylated pr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4903078/ https://www.ncbi.nlm.nih.gov/pubmed/26024026 http://dx.doi.org/10.1038/ki.2015.78 |