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Role of EPAC in cAMP-Mediated Actions in Adrenocortical Cells

Adrenocorticotropic hormone regulates adrenal steroidogenesis mainly via the intracellular signaling molecule cAMP. The effects of cAMP are principally relayed by activating protein kinase A (PKA) and the more recently discovered exchange proteins directly activated by cAMP 1 and 2 (EPAC1 and EPAC2)...

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Detalles Bibliográficos
Autores principales: Lewis, Aurélia E., Aesoy, Reidun, Bakke, Marit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904129/
https://www.ncbi.nlm.nih.gov/pubmed/27379015
http://dx.doi.org/10.3389/fendo.2016.00063