Silver nanoparticles defeat p53-positive and p53-negative osteosarcoma cells by triggering mitochondrial stress and apoptosis

Loss of function of the tumour suppressor p53 observed frequently in human cancers challenges the drug-induced apoptotic elimination of cancer cells from the body. This phenomenon is a major concern and provides much of the impetus for current attempts to develop a new generation of anticancer drugs...

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Detalles Bibliográficos
Autores principales: Kovács, Dávid, Igaz, Nóra, Keskeny, Csilla, Bélteky, Péter, Tóth, Tímea, Gáspár, Renáta, Madarász, Dániel, Rázga, Zsolt, Kónya, Zoltán, Boros, Imre M., Kiricsi, Mónika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904210/
https://www.ncbi.nlm.nih.gov/pubmed/27291325
http://dx.doi.org/10.1038/srep27902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904210/
https://www.ncbi.nlm.nih.gov/pubmed/27291325
http://dx.doi.org/10.1038/srep27902

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