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In Situ Characterization of Bak Clusters Responsible for Cell Death Using Single Molecule Localization Microscopy

Apoptosis plays a pivotal role in development and tissue homeostasis in multicellular organisms. Clustering of Bak proteins on the mitochondrial outer membrane is responsible for the induction of apoptosis by evoking a release of pro-apoptotic proteins from mitochondria into cytosol. However, how th...

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Detalles Bibliográficos
Autores principales: Nasu, Yusuke, Benke, Alexander, Arakawa, Satoko, Yoshida, Go J., Kawamura, Genki, Manley, Suliana, Shimizu, Shigeomi, Ozawa, Takeaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904369/
https://www.ncbi.nlm.nih.gov/pubmed/27293178
http://dx.doi.org/10.1038/srep27505