Long-term in vivo polychlorinated biphenyl 126 exposure induces oxidative stress and alters proteomic profile on islets of Langerhans

It has been recently proposed that exposure to polychlorinated biphenyls (PCBs) is a risk factor to type 2 diabetes mellitus (DM2). We investigated this hypothesis using long-term in vivo PCB126 exposure to rats addressing metabolic, cellular and proteomic parameters. Male Wistar rats were exposed t...

Descripción completa

Detalles Bibliográficos
Autores principales: Loiola, Rodrigo Azevedo, dos Anjos, Fabyana Maria, Shimada, Ana Lúcia, Cruz, Wesley Soares, Drewes, Carine Cristiane, Rodrigues, Stephen Fernandes, Cardozo, Karina Helena Morais, Carvalho, Valdemir Melechco, Pinto, Ernani, Farsky, Sandra Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904407/
https://www.ncbi.nlm.nih.gov/pubmed/27292372
http://dx.doi.org/10.1038/srep27882

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904407/
https://www.ncbi.nlm.nih.gov/pubmed/27292372
http://dx.doi.org/10.1038/srep27882

Ejemplares similares