PiggyBac transposon-based polyadenylation-signal trap for genome-wide mutagenesis in mice

We designed a new type of polyadenylation-signal (PAS) trap vector system in living mice, the piggyBac (PB) (PAS-trapping (EGFP)) gene trapping vector, which takes advantage of the efficient transposition ability of PB and efficient gene trap and insertional mutagenesis of PAS-trapping. The reporter...

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Detalles Bibliográficos
Autores principales: Li, Limei, Liu, Peng, Sun, Liangliang, Bin Zhou, Fei, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904408/
https://www.ncbi.nlm.nih.gov/pubmed/27292714
http://dx.doi.org/10.1038/srep27788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904408/
https://www.ncbi.nlm.nih.gov/pubmed/27292714
http://dx.doi.org/10.1038/srep27788

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