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Cyanidin suppresses amyloid beta-induced neurotoxicity by inhibiting reactive oxygen species-mediated DNA damage and apoptosis in PC12 cells

Amyloid beta (Aβ)-induced oxidative stress is a major pathologic hallmark of Alzheimer's disease. Cyanidin, a natural flavonoid compound, is neuroprotective against oxidative damage-mediated degeneration. However, its molecular mechanism remains unclear. Here, we investigated the effects of cya...

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Detalles Bibliográficos
Autores principales: Wang, Yi, Fu, Xiao-ting, Li, Da-wei, Wang, Kun, Wang, Xin-zhi, Li, Yuan, Sun, Bao-liang, Yang, Xiao-yi, Zheng, Zun-cheng, Cho, Nam Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904471/
https://www.ncbi.nlm.nih.gov/pubmed/27335564
http://dx.doi.org/10.4103/1673-5374.182707