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Methylprednisolone exerts neuroprotective effects by regulating autophagy and apoptosis

Methylprednisolone markedly reduces autophagy and apoptosis after secondary spinal cord injury. Here, we investigated whether pretreatment of cells with methylprednisolone would protect neuron-like cells from subsequent oxidative damage via suppression of autophagy and apoptosis. Cultured N2a cells...

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Detalles Bibliográficos
Autores principales: Gao, Wei, Chen, Shu-rui, Wu, Meng-yao, Gao, Kai, Li, Yuan-long, Wang, Hong-yu, Li, Chen-yuan, Li, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904476/
https://www.ncbi.nlm.nih.gov/pubmed/27335569
http://dx.doi.org/10.4103/1673-5374.182711