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Re-evaluating the role of BCR/ABL in chronic myelogenous leukemia
Chronic myelogenous leukemia (CML) requires the BCR/ABL tyrosine kinase for disease onset and maintenance. As a result, CML can be successfully treated with tyrosine kinase inhibitors (TKIs) such as imatinib. Most patients are maintained in a disease-suppressed state on daily TKI therapy for several...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904890/ https://www.ncbi.nlm.nih.gov/pubmed/27308345 http://dx.doi.org/10.4161/23723548.2014.963450 |