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The complexity of life and death decisions in mitosis

The anticancer drug taxol stabilizes microtubules and activates the spindle checkpoint, causing prolonged mitotic arrest in cancer cells. Our recent work suggests that the cellular decision to live or die following mitotic arrest is a complex process involving crosstalk between competing apoptotic a...

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Detalles Bibliográficos
Autores principales: Diaz-Martinez, Laura A, Yu, Hongtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904892/
https://www.ncbi.nlm.nih.gov/pubmed/27308420
http://dx.doi.org/10.4161/23723548.2014.969658