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Mutant p53 exerts oncogenic functions by modulating cancer cell metabolism
The metabolic function of p53 is important for its oncosuppressive function. Mutant p53 (mutp53) with gain of oncogenic function can regulate cell metabolism. Our recent study revealed a novel transcription-independent mechanism for a gain-of-function mutp53 that directly inhibits activation of aden...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904903/ https://www.ncbi.nlm.nih.gov/pubmed/27308343 http://dx.doi.org/10.4161/23723548.2014.963441 |