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Mutant p53 exerts oncogenic functions by modulating cancer cell metabolism

The metabolic function of p53 is important for its oncosuppressive function. Mutant p53 (mutp53) with gain of oncogenic function can regulate cell metabolism. Our recent study revealed a novel transcription-independent mechanism for a gain-of-function mutp53 that directly inhibits activation of aden...

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Detalles Bibliográficos
Autores principales: Zhou, Ge, Myers, Jeffrey N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904903/
https://www.ncbi.nlm.nih.gov/pubmed/27308343
http://dx.doi.org/10.4161/23723548.2014.963441