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Molecular mechanisms of mTOR regulation by stress

Tumors are prime examples of cell growth in unfavorable environments that elicit cellular stress. The high metabolic demand and insufficient vascularization of tumors cause a deficiency of oxygen and nutrients. Oncogenic mutations map to signaling events via mammalian target of rapamycin (mTOR), met...

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Detalles Bibliográficos
Autores principales: Heberle, Alexander Martin, Prentzell, Mirja Tamara, van Eunen, Karen, Bakker, Barbara Marleen, Grellscheid, Sushma Nagaraja, Thedieck, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904989/
https://www.ncbi.nlm.nih.gov/pubmed/27308421
http://dx.doi.org/10.4161/23723548.2014.970489