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The novel partnership of L-GILZ and p53: a new affair in cancer?

A recent report from our laboratory reveals how long glucocorticoid-induced leucine zipper (L-Gilz) protein binds to p53 and mouse double minute 2 homolog (Mdm2), thus dissociating the p53/Mdm2 complex and activating p53 with subsequent activation of downstream genes p21 and p53 upregulated modulato...

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Detalles Bibliográficos
Autores principales: Ayroldi, Emira, Marchetti, Cristina, Riccardi, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905020/
https://www.ncbi.nlm.nih.gov/pubmed/27308427
http://dx.doi.org/10.4161/23723556.2014.975087