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PKCλ/ι signaling—a common node for normal cellular development and breast oncogenesis

We recently demonstrated that PKCλ/ι signaling is an important contributor to breast cancer development. Strikingly, PKCλ/ι signaling is also important to balance self-renewal versus differentiation in pluripotent stem cells and is essential for embryonic development. This commentary highlights some...

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Detalles Bibliográficos
Autores principales: Paul, Arindam, Paul, Soumen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905021/
https://www.ncbi.nlm.nih.gov/pubmed/27308429
http://dx.doi.org/10.4161/23723556.2014.975076