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Necroptosis: Fifty shades of RIPKs

Apoptosis and necroptosis are 2 major, yet distinct, forms of regulated cell death. Whereas apoptosis requires caspase protease function, necroptosis requires activation of the receptor interacting protein kinases 1 (RIPK1) and RIPK3. Following activation, RIPK3 phosphorylates mixed-lineage kinase d...

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Detalles Bibliográficos
Autores principales: Ichim, Gabriel, Tait, Stephen WG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905023/
https://www.ncbi.nlm.nih.gov/pubmed/27308415
http://dx.doi.org/10.4161/23723548.2014.965638