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Functional characterization of ENPP1 reveals a link between cell cycle progression and stem-like phenotype in glioblastoma

A high-throughput phenotypic screen in glioblastoma stem-like cells (GSCs) identified a novel molecular mechanism in which ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) plays an important role in balancing the pool of nucleotides, thus maintaining GSCs in an undifferentiated proliferati...

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Detalles Bibliográficos
Autores principales: Bageritz, Josephine, Goidts, Violaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905057/
https://www.ncbi.nlm.nih.gov/pubmed/27308351
http://dx.doi.org/10.4161/23723548.2014.964028