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Functional characterization of ENPP1 reveals a link between cell cycle progression and stem-like phenotype in glioblastoma
A high-throughput phenotypic screen in glioblastoma stem-like cells (GSCs) identified a novel molecular mechanism in which ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) plays an important role in balancing the pool of nucleotides, thus maintaining GSCs in an undifferentiated proliferati...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905057/ https://www.ncbi.nlm.nih.gov/pubmed/27308351 http://dx.doi.org/10.4161/23723548.2014.964028 |