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BIM's up first

In vivo analysis of the genetic determinants of Myc-induced apoptosis reveals a specific requirement for the Bcl2 family protein Bim (Bcl2l11). Surprisingly, apoptosis induced by Myc in multiple solid tissues does not require p19Arf (Cdkn2a), whereas Puma (Bbc3) is required only in the context of se...

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Detalles Bibliográficos
Autores principales: Murphy, Daniel J., Muthalagu, Nathiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905064/
https://www.ncbi.nlm.nih.gov/pubmed/27308426
http://dx.doi.org/10.4161/23723556.2014.975083