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Role of DNA polymerase κ in the maintenance of genomic stability

To ensure high cell viability and genomic stability, cells have evolved two major mechanisms to deal with the constant challenge of DNA replication fork arrest during S phase of the cell cycle: (1) induction of the ataxia telangiectasia and Rad3-related (ATR) replication checkpoint mechanism, and (2...

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Detalles Bibliográficos
Autores principales: Pillaire, Marie-Jeanne, Bétous, Rémy, Hoffmann, Jean-Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905163/
https://www.ncbi.nlm.nih.gov/pubmed/27308312
http://dx.doi.org/10.4161/mco.29902