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Novel targets for ATM-deficient malignancies

Conventional chemo- and radiotherapies for the treatment of cancer target rapidly dividing cells in both tumor and non-tumor tissues and can exhibit severe cytotoxicity in normal tissue and impair the patient's immune system. Novel targeted strategies aim for higher efficacy and tumor specifici...

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Detalles Bibliográficos
Autores principales: Winkler, Johannes, Hofmann, Kay, Chen, Shuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905167/
https://www.ncbi.nlm.nih.gov/pubmed/27308314
http://dx.doi.org/10.4161/mco.29905