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Regulation of intestinal homeostasis and tumorigenesis by the transcriptional coregulator RIP140
Colon cancer frequently results from mutations that constitutively activate the Wnt signaling pathway, a major target being the tumor suppressor gene adenomatous polyposis coli (APC). We recently identified the transcription factor RIP140 as a new inducer of APC gene transcription that inhibits colo...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905177/ https://www.ncbi.nlm.nih.gov/pubmed/27308333 http://dx.doi.org/10.4161/23723548.2014.960761 |