The endoplasmic reticulum may be an Achilles' heel of cancer cells that have undergone an epithelial-to-mesenchymal transition

In a recent report published in Cancer Discovery we identified a novel vulnerability of cancer cells that have undergone an epithelial–mesenchymal transition (EMT) and established that the PERK branch of the unfolded protein response is constitutively activated upon EMT. In this commentary, we summa...

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Detalles Bibliográficos
Autores principales: Feng, Yu-xiong, Sokol, Ethan S, Gupta, Piyush B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905182/
https://www.ncbi.nlm.nih.gov/pubmed/27308337
http://dx.doi.org/10.4161/23723548.2014.961822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905182/
https://www.ncbi.nlm.nih.gov/pubmed/27308337
http://dx.doi.org/10.4161/23723548.2014.961822

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