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When defense turns into attack: Antiviral cytidine deaminases linked to somatic mutagenesis in HPV-associated cancer
The APOBEC3 cytidine deaminases play an important role in innate immunity but have also emerged as mediators of somatic mutations in human cancer. We recently reported a high incidence of APOBEC-mediated driver mutations in human papillomavirus-associated cancer, suggesting a key role for these enzy...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905184/ https://www.ncbi.nlm.nih.gov/pubmed/27308321 http://dx.doi.org/10.4161/mco.29914 |