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PTHrP, its receptor, and protein kinase A activation in osteosarcoma

In osteosarcoma, knockdown of the parathyroid hormone-related protein (PTHrP) receptor reduces activation through cyclic AMP-dependent protein kinase A (PKA) and substantially decreases tumor differentiation, invasion, and proliferation in vivo. These findings complement other evidence supporting a...

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Detalles Bibliográficos
Autores principales: Walkley, Carl R, Walia, Mannu K, Ho, Patricia W, Martin, T John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905201/
https://www.ncbi.nlm.nih.gov/pubmed/27308361
http://dx.doi.org/10.4161/23723548.2014.965624