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Lon protease: A key enzyme controlling mitochondrial bioenergetics in cancer

We have recently explored the in vivo functional and oncologic relevance of Lon protease (LONP1), an enzyme involved in mitochondrial quality control. We found that LONP1 is an essential protein for life and that it also performs a critical function in tumorigenesis by regulating the bioenergetics o...

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Detalles Bibliográficos
Autores principales: Quirós, Pedro M, Bárcena, Clea, López-Otín, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905204/
https://www.ncbi.nlm.nih.gov/pubmed/27308364
http://dx.doi.org/10.4161/23723548.2014.968505