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Lon protease: A key enzyme controlling mitochondrial bioenergetics in cancer
We have recently explored the in vivo functional and oncologic relevance of Lon protease (LONP1), an enzyme involved in mitochondrial quality control. We found that LONP1 is an essential protein for life and that it also performs a critical function in tumorigenesis by regulating the bioenergetics o...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905204/ https://www.ncbi.nlm.nih.gov/pubmed/27308364 http://dx.doi.org/10.4161/23723548.2014.968505 |