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Inhibitors of cell cycle checkpoints and DNA replication cause different responses in normal versus malignant urothelial cells
S-phase checkpoints are triggered in tumor cells in response to DNA replication stress caused by the tumor microenvironment or oncogenes. A recent report from our laboratory showed that tumor cells and more normal epithelial cells have a very different response to replication stress. In this Author&...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905207/ https://www.ncbi.nlm.nih.gov/pubmed/27308366 http://dx.doi.org/10.4161/23723548.2014.968508 |