Triple threat treatment: Exploiting the dependence receptor properties of metabotropic glutamate receptor 1 against melanoma

Melanoma cells that express metabotropic glutamate 1 (mGlu1) receptors depend on glutamate for their survival and proliferation. The dependence receptor properties of mGlu1 allow us to propose and justify three promising approaches for melanoma treatment: glutamate depletion, mGlu1 receptor antagoni...

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Detalles Bibliográficos
Autores principales: Gelb, Tara, Hathaway, Hannah A, Wroblewski, Jarda T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905213/
https://www.ncbi.nlm.nih.gov/pubmed/27308372
http://dx.doi.org/10.4161/23723548.2014.969163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905213/
https://www.ncbi.nlm.nih.gov/pubmed/27308372
http://dx.doi.org/10.4161/23723548.2014.969163

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