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Triple threat treatment: Exploiting the dependence receptor properties of metabotropic glutamate receptor 1 against melanoma
Melanoma cells that express metabotropic glutamate 1 (mGlu1) receptors depend on glutamate for their survival and proliferation. The dependence receptor properties of mGlu1 allow us to propose and justify three promising approaches for melanoma treatment: glutamate depletion, mGlu1 receptor antagoni...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905213/ https://www.ncbi.nlm.nih.gov/pubmed/27308372 http://dx.doi.org/10.4161/23723548.2014.969163 |