Role of G protein-coupled receptor kinase 2 in tumoral angiogenesis

Downregulation of G protein-coupled receptor kinase 2 (GRK2) in endothelial cells has recently been identified as a relevant event in the tumoral angiogenic switch. Based on the effects of altering GRK2 dosage in cell and animal models, this kinase appears to act as a hub in key signaling pathways i...

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Detalles Bibliográficos
Autores principales: Rivas, Verónica, Nogués, Laura, Reglero, Clara, Mayor, Federico, Penela, Petronila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905215/
https://www.ncbi.nlm.nih.gov/pubmed/27308373
http://dx.doi.org/10.4161/23723548.2014.969166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905215/
https://www.ncbi.nlm.nih.gov/pubmed/27308373
http://dx.doi.org/10.4161/23723548.2014.969166

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