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Sweet connections: O-GlcNAcylation links cancer cell metabolism and survival
Increased O-GlcNAcylation is emerging as a general characteristic of cancer cells that is critical for multiple oncogenic phenotypes. Recently, we demonstrated that elevated O-GlcNAcylation contributes to the metabolic shift seen in cancer through stabilization of the glycolytic regulator HIF-1α and...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905223/ https://www.ncbi.nlm.nih.gov/pubmed/27308381 http://dx.doi.org/10.4161/23723548.2014.961809 |