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The retinoblastoma protein: multitasking to suppress tumorigenesis

Tumor suppressor activity of the retinoblastoma protein pRB is preserved despite loss of interaction with E2F transcription factors (E2F) or proteins harboring a leucine-x-cysteine-x-glutamic acid motif (LxCxE, where x is any amino acid). This indicates that pRB uses several parallel pathways to sup...

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Detalles Bibliográficos
Autores principales:	Vormer, Tinke L., Hansen, Jacob B, te Riele, Hein
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2015
Materias:	Author's View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905230/ https://www.ncbi.nlm.nih.gov/pubmed/27308398 http://dx.doi.org/10.4161/23723548.2014.968062

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