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Induction of pyroptosis in colon cancer cells by LXRβ

Liver X receptors (LXRs) have been proposed to have some anticancer properties. We recently identified a new non-genomic role of LXRβ in colon cancer cells. Under LXR agonist treatment, LXRβ induces pyroptosis of these cells in vitro and in vivo, raising the possibility of targeting this isoform in...

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Detalles Bibliográficos
Autores principales: Rébé, Cédric, Derangère, Valentin, Ghiringhelli, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905240/
https://www.ncbi.nlm.nih.gov/pubmed/27308405
http://dx.doi.org/10.4161/23723548.2014.970094